TAK-659
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
| Trivial name | N/A |
| Catalog Number | S8442 |
| Molecular Formula | C17H21FN6 .HCl |
| CAS# | 1952251-28-3 |
| Inchi | InChI=1S/C17H21FN6O.ClH/c1-24-8-9(6-21-24)15-13-10(7-20-17(13)25)14(18)16(23-15)22-12-5-3-2-4-11(12)19;/h6,8,11-12H,2-5,7,19H2,1H3,(H,20,25)(H,22,23);1H/t11-,12+;/m0./s1 |
| Inchi Key | PTCFBXMEFRIEGV-ZVWHLABXSA-N |
| SMILES | CN1C=C(C=N1)C2=NC(=C(C3=C2C(=O)NC3)F)NC4CCCCC4N.Cl |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/tak-659.html |
| Additional Information | https://file.selleck.cn/downloads/struct/tak-659-chemical-structure-S8442.gif |