AZD0156
AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD0156 prevents DNA damage checkpoint activation, disrupts DNA damage repair, induces tumor cell apoptosis, and leads to cell death of ATM-overexpressing tumor cells.
| Trivial name | N/A |
| Catalog Number | S8375 |
| Molecular Formula | C26H31N5O3 |
| CAS# | 1821428-35-6 |
| Inchi | InChI=1S/C26H31N5O3/c1-29(2)11-4-12-34-24-8-6-19(16-28-24)18-5-7-22-21(15-18)25-23(17-27-22)30(3)26(32)31(25)20-9-13-33-14-10-20/h5-8,15-17,20H,4,9-14H2,1-3H3 |
| Inchi Key | AOTRIQLYUAFVSC-UHFFFAOYSA-N |
| SMILES | CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4CCOCC4)C5=CN=C(C=C5)OCCCN(C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/azd0156-azd-0156.html |
| Additional Information | https://file.selleck.cn/downloads/struct/azd0156-azd-0156-chemical-structure-s8375.gif |