HPI-4 (Ciliobrevin A)
HPI-4 (Ciliobrevin A, Hedgehog Pathway Inhibitor 4) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.
| Trivial name | Hedgehog Pathway Inhibitor 4 |
| Catalog Number | S8249 |
| Molecular Formula | C17H9Cl2N3O2 |
| CAS# | 302803-72-1 |
| Inchi | InChI=1S/C17H9Cl2N3O2/c18-9-5-6-10(13(19)7-9)15(23)12(8-20)16-21-14-4-2-1-3-11(14)17(24)22-16/h1-7,21H,(H,22,24)/b16-12+ |
| Inchi Key | SESYPWCSIZUIAS-FOWTUZBSSA-N |
| SMILES | C1=CC=C2C(=C1)C(=O)NC(=N2)C(=C(C3=C(C=C(C=C3)Cl)Cl)O)C#N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/hpi-4-ciliobrevin-a.html |
| Additional Information | https://file.selleck.cn/downloads/struct/hpi-4-ciliobrevin-a-chemical-structure-s8249.gif |