Netarsudil (AR-13324) 2HCl
Netarsudil (AR-13324) is a ROCK inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension.
Trivial name | N/A |
Catalog Number | S8226 |
Molecular Formula | C28H27N3O3.2HCl |
CAS# | 1253952-02-1 |
Inchi | InChI=1S/C28H27N3O3.2ClH/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24;;/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32);2*1H/t26-;;/m1../s1 |
Inchi Key | LDKTYVXXYUJVJM-FBHGDYMESA-N |
SMILES | CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)C(CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.Cl.Cl |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/netarsudil-ar-13324.html |
Additional Information | https://file.selleck.cn/downloads/struct/netarsudil-ar-13324-chemical-structure-s8226.gif |