CPI-637
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 values of 0.03 μM and 0.051μM for CBP and EP300 respectively in TR-FRET assay. It is highly selective against other bromodomains, displaying substantial biochemical activity only against BRD9.
| Trivial name | N/A |
| Catalog Number | S8190 |
| Molecular Formula | C22H22N6O |
| CAS# | 1884712-47-3 |
| Inchi | InChI=1S/C22H22N6O/c1-13-9-20(29)25-18-6-4-5-16(22(18)24-13)14-7-8-19-17(10-14)21(26-28(19)3)15-11-23-27(2)12-15/h4-8,10-13,24H,9H2,1-3H3,(H,25,29)/t13-/m1/s1 |
| Inchi Key | BFTKDWYIRJGJCA-CYBMUJFWSA-N |
| SMILES | CC1CC(=O)NC2=CC=CC(=C2N1)C3=CC4=C(C=C3)N(N=C4C5=CN(N=C5)C)C |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/cpi-637.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cpi-637-chemical-structure-s8190.gif |