GNF-7
GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.
| Trivial name | N/A |
| Catalog Number | S8140 |
| Molecular Formula | C28H24F3N7O2 |
| CAS# | 839706-07-9 |
| Inchi | InChI=1S/C28H24F3N7O2/c1-16-7-9-21(34-25(39)18-5-4-6-20(11-18)28(29,30)31)12-23(16)38-15-19-13-33-26(36-24(19)37(3)27(38)40)35-22-10-8-17(2)32-14-22/h4-14H,15H2,1-3H3,(H,34,39)(H,33,35,36) |
| Inchi Key | SZNYUUZOQHNEKB-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CN=C(C=C5)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gnf-7.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gnf-7-chemical-structure-s8140.gif |