Radotinib
Radotinib (IY-5511) is a selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM, used to treat Chronic Myeloid Leukemia.
| Trivial name | IY-5511 |
| Catalog Number | S8134 |
| Molecular Formula | C27H21F3N8O |
| CAS# | 926037-48-1 |
| Inchi | InChI=1S/C27H21F3N8O/c1-16-3-4-18(9-23(16)37-26-33-6-5-22(36-26)24-13-31-7-8-32-24)25(39)35-20-10-19(27(28,29)30)11-21(12-20)38-14-17(2)34-15-38/h3-15H,1-2H3,(H,35,39)(H,33,36,37) |
| Inchi Key | DUPWHXBITIZIKZ-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=NC=CN=C5 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/radotinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/radotinib-iy-5511-chemical-structure-s8134.gif |