Tubastatin A
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). Tubastatin A promotes autophagy and increases apoptosis.
| Trivial name | N/A |
| Catalog Number | S8049 |
| Molecular Formula | C20H21N3O2 |
| CAS# | 1252003-15-8 |
| Inchi | InChI=1S/C20H21N3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24) |
| Inchi Key | GOVYBPLHWIEHEJ-UHFFFAOYSA-N |
| SMILES | CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/tubastatin-a.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s8049-tubastatin-a-chemical-structure.png |