Tenovin-1
Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 is also an inhibitor of dihydroorotate dehydrogenase (DHODH).
| Trivial name | N/A |
| Catalog Number | S8000 |
| Molecular Formula | C20H23N3O2S |
| CAS# | 380315-80-0 |
| Inchi | InChI=1S/C20H23N3O2S/c1-13(24)21-16-9-11-17(12-10-16)22-19(26)23-18(25)14-5-7-15(8-6-14)20(2,3)4/h5-12H,1-4H3,(H,21,24)(H2,22,23,25,26) |
| Inchi Key | WOWJIWFCOPZFGV-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/tenovin-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Tenovin-1-chemical-structure-s8000.gif |