VPS34-IN1
Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro,which does not significantly inhibit the isoforms of class I as well as class II PI3Ks. Vps34-IN1 modulates autophagy.
| Trivial name | Vps34-IN-1 |
| Catalog Number | S7980 |
| Molecular Formula | C21H24ClN7O |
| CAS# | 1383716-33-3 |
| Inchi | InChI=1S/C21H24ClN7O/c1-21(2,30)12-26-19-25-11-15(17(29-19)9-13-3-4-13)16-6-8-24-20(28-16)27-14-5-7-23-18(22)10-14/h5-8,10-11,13,30H,3-4,9,12H2,1-2H3,(H,25,26,29)(H,23,24,27,28) |
| Inchi Key | AWNXKZVIZARMME-UHFFFAOYSA-N |
| SMILES | CC(C)(CNC1=NC=C(C(=N1)CC2CC2)C3=NC(=NC=C3)NC4=CC(=NC=C4)Cl)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/vps34-in1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/vps34-in1-chemical-structure-s7980.gif |