Zorifertinib (AZD3759)

Zorifertinib (AZD3759) is a potent, oral active, CNS-penetrant EGFR inhibitor with IC50 of 0.3 nM, 0.2 nM, and 0.2 nM for EGFR (WT), EGFR (L858R), and EGFR (exon 19Del), respectively. Phase 1.

Price Not Available 25mg Zorifertinib (AZD3759) Supplier Page

Trivial name	N/A
Catalog Number	S7971
Molecular Formula	C22H23ClFN5O3
CAS#	1626387-80-1
Inchi	InChI=1S/C22H23ClFN5O3/c1-13-11-28(2)7-8-29(13)22(30)32-19-9-14-17(10-18(19)31-3)25-12-26-21(14)27-16-6-4-5-15(23)20(16)24/h4-6,9-10,12-13H,7-8,11H2,1-3H3,(H,25,26,27)/t13-/m1/s1
Inchi Key	MXDSJQHFFDGFDK-CYBMUJFWSA-N
SMILES	CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C
Size	25mg
Supplier Page	http://www.selleckchem.com/products/azd3759.html
Additional Information	https://file.selleck.cn/downloads/struct/azd3759-chemical-structure-s7971.gif