TIC10 (ONC201)
TIC10 (ONC201) inactivates Akt and ERK to induce TNF-related apoptosis-inducing ligand (TRAIL) through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
| Trivial name | N/A |
| Catalog Number | S7963 |
| Molecular Formula | C24H26N4O |
| CAS# | 1616632-77-9 |
| Inchi | InChI=1S/C24H26N4O/c1-18-7-5-6-10-20(18)16-28-23(29)21-17-26(15-19-8-3-2-4-9-19)13-11-22(21)27-14-12-25-24(27)28/h2-10H,11-17H2,1H3 |
| Inchi Key | VLULRUCCHYVXOH-UHFFFAOYSA-N |
| SMILES | CC1=CC=CC=C1CN2C(=O)C3=C(CCN(C3)CC4=CC=CC=C4)N5C2=NCC5 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/tic-10.html |
| Additional Information | https://file.selleck.cn/downloads/struct/onc201-chemical-structure-s7963.gif |