2′,3′-cGAMP Sodium Salt (2′-3′-cyclic GMP-AMP Sodium) is produced in response to DNA in the cytoplasm in mammalian cells and binds STING with high affinity and is an effective inducer of interferon-β (IFNβ). 2′,3′-cGAMP binds to STING with Kd of 3.79 nM.