Avadomide (CC-122)

Avadomide (CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.

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Trivial name	N/A
Catalog Number	S7892
Molecular Formula	C14H14N4O3
CAS#	1015474-32-4
Inchi	InChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20)
Inchi Key	RSNPAKAFCAAMBH-UHFFFAOYSA-N
SMILES	CC1=NC2=CC=CC(=C2C(=O)N1C3CCC(=O)NC3=O)N
Size	5mg
Supplier Page	http://www.selleckchem.com/products/cc-122.html
Additional Information	https://file.selleck.cn/downloads/struct/cc-122-chemical-structure-s7892.gif