AMG319
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
| Trivial name | N/A |
| Catalog Number | S7813 |
| Molecular Formula | C21H16FN7 |
| CAS# | 1608125-21-8 |
| Inchi | InChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1 |
| Inchi Key | KWRYMZHCQIOOEB-LBPRGKRZSA-N |
| SMILES | CC(C1=C(N=C2C=C(C=CC2=C1)F)C3=CC=CC=N3)NC4=NC=NC5=C4NC=N5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/amg319.html |
| Additional Information | https://file.selleck.cn/downloads/struct/amg319-chemical-structure-s7813.gif |