SCR7
SCR7 is a specific DNA Ligase IV inhibitor, which blocks nonhomologous end-joining (NHEJ). It increases the efficiency of HDR-mediated genome editing up to 19-fold using CRISPR/Cas9 in mammalian cells and mouse embryos.
| Trivial name | N/A |
| Catalog Number | S7742 |
| Molecular Formula | C18H12N4OS |
| CAS# | 14892-97-8 |
| Inchi | InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24) |
| Inchi Key | GSRTWXVBHGOUBU-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/scr7.html |
| Additional Information | https://file.selleck.cn/downloads/struct/scr7-chemical-structure-s7742.gif |