FIIN-2
FIIN-2 is an irreversible, pan-FGFR inhibitor with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM for FGFR1/2/3/4, respectively.
Trivial name | N/A |
Catalog Number | S7714 |
Molecular Formula | C35H38N8O4 |
CAS# | 1633044-56-0 |
Inchi | InChI=1S/C35H38N8O4/c1-5-32(44)37-26-8-6-24(7-9-26)22-43-33-25(23-42(35(43)45)29-18-30(46-3)20-31(19-29)47-4)21-36-34(39-33)38-27-10-12-28(13-11-27)41-16-14-40(2)15-17-41/h5-13,18-21H,1,14-17,22-23H2, 2-4H3,(H,37,44)(H,36,38,39) |
Inchi Key | DVBPRWJMHURKHP-UHFFFAOYSA-N |
SMILES | CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C4CN(C(=O)N(C4=N3)CC5=CC=C(C=C5)NC(=O)C=C)C6=CC(=CC(=C6)OC)OC |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/fiin-2.html |
Additional Information | https://file.selleck.cn/downloads/struct/fiin-2-chemical-structure-s7714.gif |