PF-4989216
PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.
Trivial name | N/A |
Catalog Number | S7675 |
Molecular Formula | C18H13FN6OS |
CAS# | 1276553-09-3 |
Inchi | InChI=1S/C18H13FN6OS/c19-14-7-11(8-20)1-2-12(14)15-13(9-21)18(25-3-5-26-6-4-25)27-16(15)17-22-10-23-24-17/h1-2,7,10H,3-6H2,(H,22,23,24) |
Inchi Key | MUENOTXSRZEFJV-UHFFFAOYSA-N |
SMILES | C1COCCN1C2=C(C(=C(S2)C3=NC=NN3)C4=C(C=C(C=C4)C#N)F)C#N |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/pf-4989216.html |
Additional Information | https://file.selleck.cn/downloads/struct/pf-4989216-chemical-structure-s7675.gif |