Telaglenastat (CB-839)
Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. CB-839(Telaglenastat) inudces autophagy and has antitumor activity. Phase 1.
Trivial name | N/A |
Catalog Number | S7655 |
Molecular Formula | C26H24F3N7O3S |
CAS# | 1439399-58-2 |
Inchi | InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34-21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8-9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36 ,38) |
Inchi Key | PRAAPINBUWJLGA-UHFFFAOYSA-N |
SMILES | C1=CC=NC(=C1)CC(=O)NC2=NN=C(S2)CCCCC3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OC(F)(F)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/cb-839.html |
Additional Information | https://file.selleck.cn/downloads/struct/cb-839-chemical-structure-s7655.gif |