Voxtalisib (XL765)
Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
| Trivial name | SAR245409 |
| Catalog Number | S7646 |
| Molecular Formula | C13H14N6O |
| CAS# | 934493-76-2 |
| Inchi | InChI=1S/C13H14N6O/c1-3-19-11-8(7(2)16-13(14)17-11)6-9(12(19)20)10-4-5-15-18-10/h4-6H,3H2,1-2H3,(H,15,18)(H2,14,16,17) |
| Inchi Key | RGHYDLZMTYDBDT-UHFFFAOYSA-N |
| SMILES | CCN1C2=NC(=NC(=C2C=C(C1=O)C3=CC=NN3)C)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/voxtalisib-xl765-sar245409.html |
| Additional Information | https://file.selleck.cn/downloads/struct/voxtalisib-xl765-sar245409--chemical-structure-s7646.gif |