Pilaralisib (XL147)
Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.
Trivial name | N/A |
Catalog Number | S7645 |
Molecular Formula | C25H25ClN6O4S |
CAS# | 934526-89-3 |
Inchi | InChI=1S/C25H25ClN6O4S/c1-25(2,27)24(33)28-15-7-6-8-17(13-15)37(34,35)32-23-22(29-19-9-4-5-10-20(19)30-23)31-21-14-16(36-3)11-12-18(21)26/h4-14H,27H2,1-3H3,(H,28,33)(H,29,31)(H,30,32) |
Inchi Key | QINPEPAQOBZPOF-UHFFFAOYSA-N |
SMILES | CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/pilaralisib-xl147.html |
Additional Information | https://file.selleck.cn/downloads/struct/xl147-chemical-structure-s7645.gif |