3PO
3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 μM for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.
| Trivial name | 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one |
| Catalog Number | S7639 |
| CAS# | 18550-98-6 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/3po.html |
| Additional Information | https://file.selleck.cn/downloads/struct/3po-chemical-structure-s7639.gif |