Niraparib tosylate

Niraparib tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.

Price Not Available 100mg Niraparib tosylate Supplier Page
Trivial name MK 4827 tosylate
Catalog Number S7625
Molecular Formula C19H20N4O.C7H8O3S
CAS# 1038915-73-9
Inchi InChI=1S/C19H20N4O.C7H8O3S/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14;1-6-2-4-7(5-3-6)11(8,9)10/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24);2-5H,1H3,(H,8,9,10)/t14-;/m1. /s1
Inchi Key LCPFHXWLJMNKNC-PFEQFJNWSA-N
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N
Size 100mg
Supplier Page http://www.selleckchem.com/products/mk-4827-niraparib-tosylate.html
Additional Information https://file.selleck.cn/downloads/struct/mk-4827-niraparib-tosylate-chemical-structure-s7625.gif