UNC2025 HCl
UNC2025 HCl is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.
| Trivial name | UNC2025 hydrochloride |
| Catalog Number | S7576 |
| Molecular Formula | C28H41ClN6O |
| CAS# | 2070015-17-5 |
| Inchi | InChI=1S/C28H40N6O.ClH/c1-3-4-13-29-28-30-18-25-26(20-34(27(25)31-28)23-9-11-24(35)12-10-23)22-7-5-21(6-8-22)19-33-16-14-32(2)15-17-33;/h5-8,18,20,23-24,35H,3-4,9-17,19H2,1-2H3,(H,29,30,31);1H/t23?,24 -; |
| Inchi Key | NYHAEAZNSGIAPV-LCGSREGBSA-N |
| SMILES | CCCCNC1=NC=C2C(=CN(C2=N1)C3CCC(CC3)O)C4=CC=C(C=C4)CN5CCN(CC5)C.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/unc-2025.html |
| Additional Information | https://file.selleck.cn/downloads/struct/unc2025-chemical-structure-s7576.gif |