4EGI-1
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 μM. 4EGI-1 specifically inhibits the function of mTOR by blocking the activation of 4E-BP1. 4EGI-1 induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S7369 |
| Molecular Formula | C18H12Cl2N4O4S |
| CAS# | 315706-13-9 |
| Inchi | InChI=1S/C18H12Cl2N4O4S/c19-12-6-5-10(7-13(12)20)15-9-29-18(21-15)23-22-14(17(25)26)8-11-3-1-2-4-16(11)24(27)28/h1-7,9H,8H2,(H,21,23)(H,25,26)/b22-14+ |
| Inchi Key | KFRKRECSIYXARE-HYARGMPZSA-N |
| SMILES | C1=CC=C(C(=C1)CC(=NNC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O)[N+](=O)[O-] |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/4egi-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/4EGI-1-chemical-structure-s7369.gif |