Prexasertib HCl (LY2606368)

Prexasertib(LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay.

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Trivial name	N/A
Catalog Number	S7178
Molecular Formula	C18H19N7O2.2HCl
CAS#	1234015-54-3
Inchi	InChI=1S/C18H19N7O2/c1-26-14-4-2-5-15(27-7-3-6-19)18(14)13-8-16(25-24-13)23-17-11-21-12(9-20)10-22-17/h2,4-5,8,10-11H,3,6-7,19H2,1H3,(H2,22,23,24,25)
Inchi Key	DOTGPNHGTYJDEP-UHFFFAOYSA-N
SMILES	COC1=C(C(=CC=C1)OCCCN)C2=CC(=NN2)NC3=NC=C(N=C3)C#N.Cl.Cl
Size	2mg
Supplier Page	http://www.selleckchem.com/products/ly2606368.html
Additional Information	https://file.selleck.cn/downloads/struct/ly2606368-chemical-structure-s7178.gif