AZD1080
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.
| Trivial name | N/A |
| Catalog Number | S7145 |
| Molecular Formula | C19H18N4O2 |
| CAS# | 612487-72-6 |
| Inchi | InChI=1S/C19H18N4O2/c20-10-13-1-3-16-15(9-13)18(19(24)22-16)17-4-2-14(11-21-17)12-23-5-7-25-8-6-23/h1-4,9,11,22,24H,5-8,12H2 |
| Inchi Key | BLTVBQXJFVRPFK-UHFFFAOYSA-N |
| SMILES | C1COCCN1CC2=CN=C(C=C2)C3=C(NC4=C3C=C(C=C4)C#N)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/azd1080.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZD1080-chemical-structure-s7145.gif |