VU0357017 Hydrochloride

VU0357017 hydrochloride (CID-25010775) is a potent, highly selective and CNS-penetrant agonist of M1 which is a subtype of muscarinic acetylcholine receptors (mAChRs). VU0357017 hydrochloride appears to act at an allosteric site to activate the receptor with EC50 of 477 nM and Ki of 9.91 μM.

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Trivial name	CID-25010775
Catalog Number	S6795
Molecular Formula	C18H28ClN3O3
CAS#	1135242-13-5
Inchi	InChI=1S/C18H27N3O3.ClH/c1-3-24-18(23)21-12-8-15(9-13-21)19-10-11-20-17(22)16-7-5-4-6-14(16)2;/h4-7,15,19H,3,8-13H2,1-2H3,(H,20,22);1H
Inchi Key	XKJQVUIXSBOCPP-UHFFFAOYSA-N
SMILES	CCOC(=O)N1CCC(CC1)NCCNC(=O)C2=CC=CC=C2C.Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/vu0357017-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/vu0357017-hydrochloride-chemical-structure-S6795.gif