Thalidomide-O-COOH (Cereblon ligand 3)
Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3), a Thalidomide-based Cereblon (CRBN) ligand, is used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs (Proteolysis Targeting Chimera).
Trivial name | E3 ligase Ligand 3 |
Catalog Number | S6794 |
Molecular Formula | C15H12N2O7 |
CAS# | 1061605-21-7 |
Inchi | InChI=1S/C15H12N2O7/c18-10-5-4-8(13(21)16-10)17-14(22)7-2-1-3-9(12(7)15(17)23)24-6-11(19)20/h1-3,8H,4-6H2,(H,19,20)(H,16,18,21) |
Inchi Key | ZVWIXIGBWIEDFO-UHFFFAOYSA-N |
SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCC(=O)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/thalidomide-o-cooh.html |
Additional Information | https://file.selleck.cn/downloads/struct/thalidomide-o-cooh-chemical-structure-s6794.gif |