Bozitinib
Bozitinib is a highly selective ATP-competitive c-Met inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) selectively inhibits MET-altered tumor cells in preclinical models.
| Trivial name | PLB-1001, CBT-101, APL-101, CBI-3103 |
| Catalog Number | S6762 |
| Molecular Formula | C20H15F3N8 |
| CAS# | 1440964-89-5 |
| Inchi | InChI=1S/C20H15F3N8/c1-29-9-11-6-14(15(21)7-17(11)27-29)20(22,23)19-26-25-18-5-4-16(28-31(18)19)12-8-24-30(10-12)13-2-3-13/h4-10,13H,2-3H2,1H3 |
| Inchi Key | QHXLXUIZUCJRKV-UHFFFAOYSA-N |
| SMILES | CN1C=C2C=C(C(=CC2=N1)F)C(C3=NN=C4N3N=C(C=C4)C5=CN(N=C5)C6CC6)(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/bozitinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bozitinib-chemical-structure-s6762.gif |