JG98
JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive annexin staining. JG-98 exhibits anticancer activity.
| Trivial name | N/A |
| Catalog Number | S6721 |
| Molecular Formula | C24H21Cl2N3OS3 |
| CAS# | 1456551-16-8 |
| Inchi | InChI=1S/C24H21ClN3OS3.ClH/c1-3-28-21(14-20-27(11-12-30-20)15-16-7-5-4-6-8-16)32-22(23(28)29)24-26(2)18-10-9-17(25)13-19(18)31-24;/h4-14H,3,15H2,1-2H3;1H/q+1;/p-1/b24-22+; |
| Inchi Key | AUPPGWXGMILTRB-HDPAMLMOSA-M |
| SMILES | CCN1C(=CC2=[N+](C=CS2)CC3=CC=CC=C3)SC(=C4N(C5=C(S4)C=C(C=C5)Cl)C)C1=O.[Cl-] |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/jg98.html |
| Additional Information | https://file.selleck.cn/downloads/struct/jg98-chemical-structure-s6721.gif |