L-779450
L-779450 is a highly potent low nanomolar inhibitor of B-raf with IC50 of 10 nM and Kd of 2.4 nM.
Trivial name | L-779,450 |
Catalog Number | S6680 |
Molecular Formula | C20H14ClN3O |
CAS# | 303727-31-3 |
Inchi | InChI=1S/C20H14ClN3O/c21-16-7-6-15(12-17(16)25)19-18(13-8-10-22-11-9-13)23-20(24-19)14-4-2-1-3-5-14/h1-12,25H,(H,23,24) |
Inchi Key | WXJLXRNWMLWVFB-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC(=C(C=C4)Cl)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/l-779450.html |
Additional Information | https://file.selleck.cn/downloads/struct/l-779450-chemical-structure-s6680.gif |