E7046 (ER-886406)
E7046 (ER-886406, Palupiprant, AN0025) is a selective inhibitor of the prostaglandin E2 (PGE2) receptor EP4 with IC50 of 13.5 nM and Ki of 23.14 nM.
| Trivial name | Palupiprant, AN0025 |
| Catalog Number | S6649 |
| Molecular Formula | C22H18F5N3O4 |
| CAS# | 1369489-71-3 |
| Inchi | InChI=1S/C22H18F5N3O4/c1-11(12-6-8-13(9-7-12)21(32)33)28-19(31)16-17(18(23)24)29-30(2)20(16)34-15-5-3-4-14(10-15)22(25,26)27/h3-11,18H,1-2H3,(H,28,31)(H,32,33)/t11-/m0/s1 |
| Inchi Key | MKLKAQMPKHNQPR-NSHDSACASA-N |
| SMILES | CC(C1=CC=C(C=C1)C(=O)O)NC(=O)C2=C(N(N=C2C(F)F)C)OC3=CC=CC(=C3)C(F)(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/e7046.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7046-chemical-structure-s6649.gif |