AMG-333
AMG-333 is a potent and highly selective antagonist of TRPM8 with IC50 values of 13 nM and 30 nM for human TRPM8 and rat TRPM8.
Trivial name | N/A |
Catalog Number | S6638 |
Molecular Formula | C20H12F5N3O4 |
CAS# | 1416799-28-4 |
Inchi | InChI=1S/C20H12F5N3O4/c21-12-2-1-7-26-17(12)16(10-4-6-15(13(22)8-10)32-20(23,24)25)28-18(29)14-5-3-11(9-27-14)19(30)31/h1-9,16H,(H,28,29)(H,30,31)/t16-/m0/s1 |
Inchi Key | QEBYISWYMFIXOZ-INIZCTEOSA-N |
SMILES | C1=CC(=C(N=C1)C(C2=CC(=C(C=C2)OC(F)(F)F)F)NC(=O)C3=NC=C(C=C3)C(=O)O)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/amg-333.html |
Additional Information | https://file.selleck.cn/downloads/struct/amg-333-chemical-structure-s6638.gif |