THZ531
THZ531 is a selective covalent inhibitor of CDK12 and CDK13 with IC50 values of 158 and 69 nM, respectively.
| Trivial name | N/A |
| Catalog Number | S6595 |
| Molecular Formula | C30H32ClN7O2 |
| CAS# | 1702809-17-3 |
| Inchi | InChI=1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,8-14,17-18,22,32H,5,7,15-16,19H2,1-2H3,(H,34 ,39)(H,33,35,36)/b10-6+/t22-/m1/s1 |
| Inchi Key | RUBYHLPRZRMTJO-MOVYNIQHSA-N |
| SMILES | CN(C)CC=CC(=O)NC1=CC=C(C=C1)C(=O)N2CCCC(C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/thz531.html |
| Additional Information | https://file.selleck.cn/downloads/struct/thz531-chemical-structure-s6595.gif |