AG 555
AG-555 (Tyrphostin B46) is an inhibitor of tyrosine kinase, interacts directly with topoisomerase I, thus preventing DNA relaxation. It inhibits EGFR with an IC50 of 0.7 μM.
| Trivial name | Tyrphostin B46 |
| Catalog Number | S6525 |
| Molecular Formula | C19H18N2O3 |
| CAS# | 133550-34-2 |
| Inchi | InChI=1S/C19H18N2O3/c20-13-16(11-15-8-9-17(22)18(23)12-15)19(24)21-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,22-23H,4,7,10H2,(H,21,24)/b16-11+ |
| Inchi Key | GSQOBTOAOGXIFL-LFIBNONCSA-N |
| SMILES | C1=CC=C(C=C1)CCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ag555.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ag-555-chemical-structure-s6525.gif |