HMN-176
HMN-176 is an active metabolite of HMN-214, which has a potent antitumor activity in mouse xenograft models. HMN-176 effectively inhibits PLK-1 by interference with its normal subcellular spatial distribution at centrosomes and along the cytoskeletal structure.
| Trivial name | N/A |
| Catalog Number | S5807 |
| Molecular Formula | C20H18N2O4S |
| CAS# | 173529-10-7 |
| Inchi | InChI=1S/C20H18N2O4S/c1-26-18-8-10-19(11-9-18)27(24,25)21-20-5-3-2-4-17(20)7-6-16-12-14-22(23)15-13-16/h2-15,21H,1H3/b7-6+ |
| Inchi Key | LBPNULPSVCDYRF-VOTSOKGWSA-N |
| SMILES | COC1=CC=C(C=C1)S(=O)(=O)N=C2C=CC=CC2=CC=C3C=CN(C=C3)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/hmn-176.html |
| Additional Information | https://file.selleck.cn/downloads/struct/hmn-176-chemical-structure-s5807.gif |