Motesanib (AMG-706)
Motesanib (AMG-706) is an orally bioavailable receptor tyrosine kinase inhibitor with IC50 values of 2 nM, 3 nM, 6 nM, 8 nM, 84 nM, 59 nM for VEGFR1, VEGFR2, VEGFR3, Kit, PDGFR and Ret, respectively.
Trivial name | N/A |
Catalog Number | S5793 |
Molecular Formula | C22H23N5O |
CAS# | 453562-69-1 |
Inchi | InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28) |
Inchi Key | RAHBGWKEPAQNFF-UHFFFAOYSA-N |
SMILES | CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/motesanib-amg-706.html |
Additional Information | https://file.selleck.cn/downloads/struct/motesanib-amg-706-chemical-structure-s5793.gif |