Bedaquiline
Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).
| Trivial name | TMC-207, R207910 |
| Catalog Number | S5623 |
| Molecular Formula | C22H24F3N3O3 |
| CAS# | 843663-66-1 |
| SMILES | CN1C=C(C=C(C)C1=O)C2=CC=C3N=C(C4CCOCC4)[N](CCOC(F)(F)F)C3=C2 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/bedaquiline.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bedaquiline-chemical-structure-s5623.gif |