Rolapitant
Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.
| Trivial name | SCH-619734 |
| Catalog Number | S5476 |
| Molecular Formula | C11H21N.ClH |
| CAS# | 552292-08-7 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | Cl.CNC1(C)C2CCC(C2)C1(C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/rolapitant.html |
| Additional Information | https://file.selleck.cn/downloads/struct/rolapitant-chemical-structure-s5476.gif |