Dasabuvir (ABT-333)
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 and 10.7 nM. It is at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases.
Trivial name | N/A |
Catalog Number | S5402 |
Molecular Formula | C26H27N3O5S |
CAS# | 1132935-63-7 |
Inchi | InChI=1S/C26H27N3O5S/c1-26(2,3)22-15-20(29-11-10-23(30)27-25(29)31)14-21(24(22)34-4)18-7-6-17-13-19(28-35(5,32)33)9-8-16(17)12-18/h6-15,28H,1-5H3,(H,27,30,31) |
Inchi Key | NBRBXGKOEOGLOI-UHFFFAOYSA-N |
SMILES | CC(C)(C)C1=CC(=CC(=C1OC)C2=CC3=C(C=C2)C=C(C=C3)NS(=O)(=O)C)N4C=CC(=O)NC4=O |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/dasabuvir-abt-333.html |
Additional Information | https://file.selleck.cn/downloads/struct/S5402 Dasabuvir(ABT-333).gif |