Safinamide
Safinamide (EMD-1195686, PNU-15774E) is an orally active, selective, reversiblemonoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.
Trivial name | EMD-1195686, PNU-15774E |
Catalog Number | S5357 |
Molecular Formula | C17H19FN2O2 |
CAS# | 133865-89-1 |
Inchi | InChI=1S/C17H19FN2O2/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14/h2-9,12,20H,10-11H2,1H3,(H2,19,21)/t12-/m0/s1 |
Inchi Key | NEMGRZFTLSKBAP-LBPRGKRZSA-N |
SMILES | CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/safinamide.html |
Additional Information | https://file.selleck.cn/downloads/struct/safinamide-chemical-structure-s5357.gif |