NU2058
NU2058 (O(6)-Cyclohexylmethylguanine) is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay. It also potentiates melphalan (DMF 2.3), and monohydroxymelphalan (1.7), but not temozolomide or ionising radiation.
| Trivial name | O(6)-Cyclohexylmethylguanine |
| Catalog Number | S5316 |
| Molecular Formula | C12H17N5O |
| CAS# | 161058-83-9 |
| Inchi | InChI=1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17) |
| Inchi Key | MWGXGTJJAOZBNW-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)COC2=NC(=NC3=C2NC=N3)N |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/nu2058.html |
| Additional Information | https://file.selleck.cn/downloads/struct/nu2058-chemical-structure-s5316.gif |