NU2058
NU2058 (O(6)-Cyclohexylmethylguanine) is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay. It also potentiates melphalan (DMF 2.3), and monohydroxymelphalan (1.7), but not temozolomide or ionising radiation.
| Trivial name | O(6)-Cyclohexylmethylguanine |
| Catalog Number | S5316 |
| Molecular Formula | C13H10O5 |
| CAS# | 161058-83-9 |
| Inchi | InChI=1S/C13H10O5/c1-15-10-7-3-4-9(14)18-12(7)13(16-2)11-8(10)5-6-17-11/h3-6H,1-2H3 |
| Inchi Key | DFMAXQKDIGCMTL-UHFFFAOYSA-N |
| SMILES | COC1=C2C=COC2=C(C3=C1C=CC(=O)O3)OC |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/nu2058.html |
| Additional Information | https://file.selleck.cn/downloads/struct/nu2058-chemical-structure-s5316.gif |