Zoledronic acid monohydrate
Zoledronic acid (Zoledronate, CGP-4244) monohydrate, a nitrogen-containing bisphosphonate, is a potent osteoclast inhibitor which induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho.
| Trivial name | zoledronate monohydrate, CGP-4244 monohydrate |
| Catalog Number | S5244 |
| Molecular Formula | C32H42O16 |
| CAS# | 165800-06-6 |
| Inchi | InChI=1S/C32H42O16/c1-41-19-7-13(3-5-17(19)45-31-27(39)25(37)23(35)21(9-33)47-31)29-15-11-44-30(16(15)12-43-29)14-4-6-18(20(8-14)42-2)46-32-28(40)26(38)24(36)22(10-34)48-32/h3-8,15-16,21-40H,9-12H2,1- 2H3/t15-,16-,21+,22+,23+,24+,25-,26-,27+,28+,29+,30+,31+,32+/m0/s1 |
| Inchi Key | ZJSJQWDXAYNLNS-FUPWJLLWSA-N |
| SMILES | COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC)OC6C(C(C(C(O6)CO)O)O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/zoledronic-acid-monohydrate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/zoledronic-acid-monohydrate-chemical-structure-s5244.gif |