PD 169316
PD 169316 is a potent, selective and cell-permeable p38 MAP kinase inhibitor with IC50 of 89 nM. PD169316 abrogates signaling initiated by both TGFbeta and Activin A. PD169316 shows antiviral activity against Enterovirus71.
Trivial name | N/A |
Catalog Number | S5183 |
Molecular Formula | C20H13FN4O2 |
CAS# | 152121-53-4 |
Inchi | InChI=1S/C20H13FN4O2/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(8-4-15)25(26)27/h1-12H,(H,23,24) |
Inchi Key | BGIYKDUASORTBB-UHFFFAOYSA-N |
SMILES | C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)[N+](=O)[O-] |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/pd-169316.html |
Additional Information | https://file.selleck.cn/downloads/struct/pd-169316-chemical-structure-s5183.gif |