Gefitinib hydrochloride
Gefitinib (ZD1839) is an EGFR inhibitor with IC50s of 15.5 nM and 823.3 nM for WT EGFR and EGFR (858R/T790M), respectively.
| Trivial name | ZD1839 hydrochloride |
| Catalog Number | S5098 |
| Molecular Formula | C29H36O16 |
| CAS# | 184475-55-6 |
| Inchi | InChI=1S/C29H36O16/c30-11-19-22(37)23(38)24(39)29(42-19)45-27-25(40)28(41-8-7-14-2-5-16(33)18(35)10-14)43-20(12-31)26(27)44-21(36)6-3-13-1-4-15(32)17(34)9-13/h1-6,9-10,19-20,22-35,37-40H,7-8,11-12H2/b 6-3+/t19-,20-,22-,23+,24-,25-,26-,27-,28-,29+/m1/s1 |
| Inchi Key | KFEFLPDKISUVNR-QJEHNBJNSA-N |
| SMILES | C1=CC(=C(C=C1CCOC2C(C(C(C(O2)CO)OC(=O)C=CC3=CC(=C(C=C3)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gefitinib-hydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gefitinib-hydrochloride-chemical-structure-s5098.gif |
