SC-514
SC-514 (GK 01140) is an orally active, ATP-competitive IKK-2 inhibitor with IC50 of 3-12 μM, blocks NF-κB-dependent gene expression, does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.
| Trivial name | GK 01140 |
| Catalog Number | S4907 |
| Molecular Formula | C9H8N2OS2 |
| CAS# | 354812-17-2 |
| Inchi | InChI=1S/C9H8N2OS2/c10-6-3-7(5-1-2-13-4-5)14-8(6)9(11)12/h1-4H,10H2,(H2,11,12) |
| Inchi Key | BMUACLADCKCNKZ-UHFFFAOYSA-N |
| SMILES | C1=CSC=C1C2=CC(=C(S2)C(=O)N)N |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/sc-514.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SC-514-chemical-structure-s4907.gif |