Lesinurad
Lesinurad (RDEA-594) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.
| Trivial name | RDEA 594, RDEA-594, RDEA594 |
| Catalog Number | S4640 |
| Molecular Formula | C22H33ClN2O2 |
| CAS# | 878672-00-5 |
| Inchi | InChI=1S/C22H33N2O2.ClH/c1-6-21-23(5)18-9-7-8-10-19(18)24(21)14-22(25)26-20-13-16(4)11-12-17(20)15(2)3;/h7-10,15-17,20H,6,11-14H2,1-5H3;1H/q+1;/p-1/t16-,17+,20-;/m1./s1 |
| Inchi Key | UBWVTCCKVGOTBG-VYZBTARASA-M |
| SMILES | CCC1=[N+](C2=CC=CC=C2N1CC(=O)OC3CC(CCC3C(C)C)C)C.[Cl-] |
| Size | 20mg |
| Supplier Page | http://www.selleckchem.com/products/lesinurad.html |
| Additional Information | https://file.selleck.cn/downloads/struct/lesinurad-chemical-structure-s4640.gif |