Vinblastine sulfate
Vinblastine sulfate inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay, used to treat certain kinds of cancer. Vinblastine sulfate induces autophagy and apoptosis.
Trivial name | NSC-49842, Vincaleukoblastine, 29060-LE |
Catalog Number | S4505 |
Molecular Formula | C46H58N4O9.H2SO4 |
CAS# | 143-67-9 |
Inchi | InChI=1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)5 1)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44?,45-,46-;/m0./s1 |
Inchi Key | KDQAABAKXDWYSZ-IEGOSMDXSA-N |
SMILES | CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/vinblastine-sulfate.html |
Additional Information | https://file.selleck.cn/downloads/struct/vinblastine-sulfate-chemical-structure-s4505.gif |