Ginsenoside Rd
Ginsenoside Rd (Panaxoside Rd, Sanchinoside Rd), a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.
| Trivial name | Panaxoside Rd, Sanchinoside Rd |
| Catalog Number | S3931 |
| Molecular Formula | C10H23BN2O6S |
| CAS# | 52705-93-8 |
| Inchi | InChI=1S/C9H19BN2O3.CH4O3S/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15;1-5(2,3)4/h6-8,14-15H,3-5,11H2,1-2H3;1H3,(H,2,3,4)/t7-,8-;/m0./s1 |
| Inchi Key | OXYYOEIGQRXGPI-WSZWBAFRSA-N |
| SMILES | B(C1CCCN1C(=O)C(C(C)C)N)(O)O.CS(=O)(=O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ginsenoside-rd.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ginsenoside-rd-chemical-structure-s3931.gif |